Expresión de búsqueda: TRANSCRIPTION FACTOR HES-1 
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Descriptor Inglés:   Transcription Factor HES-1 
Descriptor Español:   Factor de Transcripción HES-1 
Descriptor Portugués:   Fatores de Transcrição HES-1 
Sinónimos Inglés:   Hairy and Enhancer of Split 1 Protein
Hairy-Like Transcription Factor
HES-1, Transcription Factor
Hairy Like Transcription Factor
Transcription Factor HES 1
Transcription Factor, Hairy-Like  
Categoría:   D12.776.260.103.844
D12.776.930.125.844
Definición Inglés:   A basic-helix-loop-helix transcription factor that functions as a transcriptional repressor for genes transcribed by bHLH proteins. For example, it may negatively regulate MYOGENESIS by inhibiting MyoD1 and ASH1 proteins. It is also required for the stability of FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS and their localization to the cell nucleus in response to DNA DAMAGE. 
Nota Histórica Inglés:   2017 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   56597 
Identificador Único:   D000072056 

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